Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the wordpress-seo domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/html/wp-includes/functions.php on line 6260 Slimaluma Could Inhibit Hyperplastic Obesity - Nutraceuticals World

What are you searching for?

Sign in
Research

Slimaluma Could Inhibit Hyperplastic Obesity

Author Image

By: Sean Moloughney

Editor, Nutraceuticals World

A study published in the journal Food & Nutrition Sciences indicates Slimaluma, a standardized extract of the plant Caralluma fimbriata, from Gencor Nutrients, has the potential to inhibit hyperplastic obesity by inhibiting pre-adipocyte cell division. 

Mouse 3T3-L1 pre-adipocyte cell line samples were treated with different concentrations of the extract standardized against its pregnane glycoside content. The cells were counted at 12-hour intervals, and their viability tested using the MTT assay. The treated cells were subjected to direct and indirect immunofluorescent assays for cyclin D1. Slimaluma inhibited 3T3-L1 cell growth in a dose and duration-dependent manner, with results comparable to those produced by hydroxyurea.

Researchers concluded the Slimaluma appears to inhibit pre-adipocyte cell division by interfering with a mechanism preceding the import of cyclin D1-CDk4/6 complex into the nucleus during the early G1 phase of the cell cycle, suggesting that it has the potential to inhibit hyperplastic obesity. For further information: www.gencorpacific.com

Add us as a preferred source on Google

Get the latest Nutraceuticals World news, insights and analysis in your Google Search and AI experiences.

Add Nutraceuticals World as a preferred source on Google (opens in a new tab)

Keep Up With Our Content. Subscribe To Nutraceuticals World Newsletters